Bosses: Such as Commander Lucius, Warden Krieg, Herald Of The Flame, or The Amalgamation.

Heroic creatures: These aetherials and aether corruptions are marked with the star next to their name and typically have extra titles such as Azar The Wrathful, Aetheron The Plaguebearer, or Kamladris the Rimeheart.

Tainted Brain Matter will drop randomly from these creature types: Instead on relying on chests to effectively farm Tainted Brain Matter, your best bet is to go anywhere where aetherials and aether corruption creatures spawn at a high level. The locked chests that have to be opened with dynamite in Deadman's Gulch also occasionally drop them.įrankly, the percentage chance on chests is low enough that its more of a 'Hey, cool, it finally dropped,' than anything that can be reliably farmed, however, so this isn't the best way to go about finding rare crafting ingredients. In particular, I've had success finding Tainted Brain Matter after defeating The Master Of Flesh and opening the chests labeled as The Master's Trove at the end of Ashes of Malmouth.

Farming specific aetherials and aether corruptionsĪll of the rare crafting materials such as Tainted Brain Matter, Blood Of Ch'thon, and Ancient Hearts (very) occasionally drop from heroic chests, end boss chests, and one shot chests.

There are three main ways to acquire Tainted Brain Matter, which we'll cover in depth below:

Tainted Brain Matter is one rare material that players have trouble finding, especially as they level up and outpace the starting normal mode difficulty.

Grim dawn nemesis spawns